Boardman L A, Peipert J F, Cooper A S, Cu-Uvin S, Flanigan T, Raphael S I
Department of Obstetrics and Gynecology, Women and Infants' Hospital, Providence, Rhode Island.
Obstet Gynecol. 1994 Dec;84(6):1016-20.
To evaluate the rate of discrepancy between cytology and histology in a referral-based population of human immunodeficiency virus (HIV)-positive women compared to HIV-negative women and women whose HIV status was unknown.
From January 1, 1990 to December 31, 1993, approximately 830 women underwent evaluation at Women and Infants' Hospital colposcopy clinic. Women who had histologic diagnosis and recent cytologic evaluation during this interval (N = 678) were selected for study. Forty-one HIV-positive women were compared to 228 HIV-negative women and 409 women whose HIV status was unknown.
Of the 41 HIV-positive women, seven (17%) were noted to have a discrepancy between cytologic and histologic findings. In HIV-negative and HIV-unknown women, 15% (34 of 228) and 22% (91 of 409) were discrepant, respectively. Using HIV-negative women as the reference group, the relative risk of cytologic-histologic discrepancy was 1.1 (95% confidence interval [CI] 0.51-2.41) for HIV-positive women and 1.5 (95% CI 1.04-2.14) for women whose HIV status was unknown.
Human immunodeficiency virus-positive women referred for colposcopic evaluation have no more cytologic-histologic discrepancy than HIV-negative women or women whose HIV status is unknown.
评估在以转诊为基础的人群中，与HIV阴性女性及HIV感染状况未知的女性相比，HIV阳性女性细胞学检查结果与组织学检查结果之间的差异率。
1990年1月1日至1993年12月31日期间，约830名女性在妇女和婴儿医院阴道镜诊所接受评估。选取在此期间有组织学诊断且近期进行过细胞学评估的女性（N = 678）进行研究。将41名HIV阳性女性与228名HIV阴性女性及409名HIV感染状况未知的女性进行比较。
41名HIV阳性女性中，有7名（17%）的细胞学检查结果与组织学检查结果存在差异。在HIV阴性及HIV感染状况未知的女性中，差异率分别为15%（228名中的34名）和22%（409名中的91名）。以HIV阴性女性作为参照组，HIV阳性女性细胞学与组织学结果差异的相对风险为1.1（95%置信区间[CI] 0.51 - 2.41），HIV感染状况未知的女性为1.5（95% CI 1.04 - 2.14）。
因阴道镜检查而转诊的HIV阳性女性，其细胞学与组织学结果的差异并不比HIV阴性女性或HIV感染状况未知的女性更多。
