Elliott J P, Sawyer A T, Radin T G, Strong R E
Phoenix Perinatal Associates, Arizona.
Obstet Gynecol. 1994 Dec;84(6):1025-7.
To evaluate the safety and outcome of large-volume therapeutic amniocentesis in the treatment of hydramnios.
Therapeutic amniocentesis was defined as an attempt to remove enough amniotic fluid (AF) in pregnancies complicated by symptomatic hydramnios to leave a normal volume of AF (AF index less than 25 cm). This report includes all therapeutic amniocenteses that were performed at Good Samaritan Regional Medical Center in Phoenix, Arizona, from 1988-1993.
Ninety-four patients had 200 therapeutic amniocenteses. The most common condition treated with therapeutic amniocentesis was twin-twin transfusion syndrome (36 patients). The mean volume of fluid removed was 1666 +/- 1245 mL (mean +/- standard deviation). The median volume of fluid removed was 1500 mL (range 350-10,000). The fluid was removed at a mean rate of 54 +/- 22 mL/minute. Complications were limited to one patient with ruptured membranes one day after therapeutic amniocentesis, one patient who developed chorioamnionitis, and one patient with an anencephalic fetus who had an abruption following removal of 10,200 mL of fluid.
Large-volume therapeutic amniocentesis can be used to treat hydramnios, with a 1.5% complication rate.
评估大容量治疗性羊膜腔穿刺术治疗羊水过多的安全性及结局。
治疗性羊膜腔穿刺术定义为在因有症状的羊水过多而并发的妊娠中，试图抽出足够量的羊水，使羊水量恢复正常（羊水指数小于25cm）。本报告纳入了1988年至1993年在亚利桑那州凤凰城的撒玛利亚地区医疗中心进行的所有治疗性羊膜腔穿刺术。
94例患者接受了200次治疗性羊膜腔穿刺术。治疗性羊膜腔穿刺术治疗的最常见疾病是双胎输血综合征（36例患者）。抽出的平均羊水量为1666±1245mL（均值±标准差）。抽出羊水量的中位数为1500mL（范围350 - 10,000）。抽液平均速率为54±22mL/分钟。并发症仅限于1例在治疗性羊膜腔穿刺术后1天胎膜破裂的患者、1例发生绒毛膜羊膜炎的患者以及1例无脑儿胎儿在抽出10,200mL液体后发生胎盘早剥的患者。
大容量治疗性羊膜腔穿刺术可用于治疗羊水过多，并发症发生率为1.5%。
