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双胎输血综合征中的羊膜腔内减压

Intra-amniotic pressure reduction in twin-twin transfusion syndrome.

作者信息

Garry D, Lysikiewicz A, Mays J, Canterino J, Tejani N

机构信息

Department of Obstetrics and Gynecology, New York Medical College, Westchester County Medical Center, Valhalla, USA.

出版信息

J Perinatol. 1998 Jul-Aug;18(4):284-6.

PMID:9730198
Abstract

OBJECTIVE

Our purpose was to measure intra-amniotic pressure before and after decompression amniocentesis in twin-twin transfusion syndrome.

STUDY DESIGN

Intra-amniotic pressures were measured during decompression amniocentesis on 18 occasions in 5 pregnancies complicated by twin-twin transfusion syndrome. The intra-amniotic pressure was determined with a water manometer before and after removal of amniotic fluid. For comparison, intra-amniotic pressure was determined in 10 uncomplicated gestations.

RESULTS

Initial intra-amniotic pressures in twin-twin transfusion gestations (mean, 17.2 +/- 5.2 cm H2O; range, 5.5 to 33.0 cm H2O) were higher than those of the uncomplicated gestations (mean, 8.4 +/- 3.3 cm H2O; range, 3.5 to 13.5 cm H2O; p < 0.002). Intra-amniotic pressures following therapeutic amniocentesis (mean, 10.9 +/- 5.1 cm H2O; range, 3.5 to 23.0 cm H2O) were not different from those of the uncomplicated gestations (p = 0.16).

CONCLUSION

The intra-amniotic pressure in twin-twin transfusion gestations is higher than that of the uncomplicated gestation. Decompression amniocentesis reduces intra-amniotic pressure to that of the uncomplicated gestation.

摘要

目的

我们的目的是测量双胎输血综合征减压羊膜腔穿刺术前、后的羊膜腔内压力。

研究设计

在5例并发双胎输血综合征的妊娠中,进行了18次减压羊膜腔穿刺术,并测量羊膜腔内压力。在抽取羊水前后,用水压计测定羊膜腔内压力。作为对照,在10例正常妊娠中测定羊膜腔内压力。

结果

双胎输血综合征妊娠的初始羊膜腔内压力(平均值为17.2±5.2 cmH₂O;范围为5.5至33.0 cmH₂O)高于正常妊娠(平均值为8.4±3.3 cmH₂O;范围为3.5至13.5 cmH₂O;p<0.002)。治疗性羊膜腔穿刺术后的羊膜腔内压力(平均值为10.9±5.1 cmH₂O;范围为3.5至23.0 cmH₂O)与正常妊娠无差异(p = 0.16)。

结论

双胎输血综合征妊娠的羊膜腔内压力高于正常妊娠。减压羊膜腔穿刺术可将羊膜腔内压力降至正常妊娠水平。

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Intra-amniotic pressure reduction in twin-twin transfusion syndrome.双胎输血综合征中的羊膜腔内减压
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Fetal urine and amniotic fluid in monochorionic twins with twin-twin transfusion syndrome: simulations of therapy.单绒毛膜双胎妊娠合并双胎输血综合征时的胎儿尿液与羊水:治疗模拟
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Treatment of twin-twin transfusion syndrome.
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Obstet Gynecol. 1991 Apr;77(4):537-40.
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Large-volume therapeutic amniocentesis in the treatment of hydramnios.大容量治疗性羊膜腔穿刺术治疗羊水过多。
Obstet Gynecol. 1994 Dec;84(6):1025-7.
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Diagnosis, pathophysiology, and treatment of chronic twin-to-twin transfusion syndrome.慢性双胎输血综合征的诊断、病理生理学及治疗
Fetal Diagn Ther. 1994 Sep-Oct;9(5):283-90. doi: 10.1159/000263949.
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Twin-twin transfusion syndrome: intraamniotic pressure measurement in the assessment of volume reduction at serial amniocenteses.双胎输血综合征:在连续羊膜腔穿刺减容术中通过测量羊膜腔内压力进行评估
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Perinatal morbidity and mortality rates in severe twin-twin transfusion syndrome: results of the International Amnioreduction Registry.重度双胎输血综合征的围产期发病率和死亡率:国际羊水减量登记处的结果
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