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新生儿脑干听觉诱发电位(ABR)中听觉通路的成熟。

Maturation of the acoustic path-way in brain stem responses (ABR) in neonates.

作者信息

Reroń E, Sekuła J

机构信息

Otolaryngological Clinic, Academy of Medicine in Cracow.

出版信息

Otolaryngol Pol. 1994;48(4):363-9.

PMID:7970783
Abstract

In a group of 130 tested children, 102 of whom had a property evaluated brain stem responses, we tested the influence of newborn maturation on values of response parameters, their configuration and threshold values. It was shown that newborn maturation lowers in a statistically significant way the threshold values of acoustic stimulus. Also, the configuration of the monitoring changes with age of child tested. Newborn maturation increases the frequency of occurrence of waves II, IV and VI though decreases of incidence IV/V complex. In the group of the youngest pre-term babies IV/V complex were present in 50% of the cases whereas in the group of newborns carried to term its present could be verified only in 5-11% of cases. Newborn maturity also in an essential way shortening the latent time consecutive waves as well as central conduction time determining by interpeak latency I-V. Coefficient correlation values for those parameters shows a negative statistical significance correlation. That is, a decreasing of average values of those parameters with maturation of the newborn. It was also shown that structures of the hearing pathway responsible for generation of early and late components of the brain stem responses mature at different time. Peripheral structure of the hearing pathway are significantly more mature at birth than are central structures.

摘要

在一组130名接受测试的儿童中,其中102名儿童进行了脑干听觉诱发电位测试,我们研究了新生儿发育对反应参数值、其波形形态和阈值的影响。结果表明,新生儿发育在统计学上显著降低了听觉刺激的阈值。此外,监测的波形形态会随着受测儿童的年龄而变化。新生儿发育增加了波II、IV和VI的出现频率,尽管IV/V复合波的发生率降低。在最年幼的早产儿组中,IV/V复合波在50%的病例中出现,而在足月儿组中,仅在5%-11%的病例中能检测到。新生儿成熟还显著缩短了连续波的潜伏期以及由峰间潜伏期I-V确定的中枢传导时间。这些参数的系数相关值显示出负的统计学显著相关性。也就是说,随着新生儿的成熟,这些参数的平均值降低。研究还表明,负责产生脑干听觉诱发电位早期和晚期成分的听觉通路结构在不同时间成熟。听觉通路的外周结构在出生时比中枢结构明显更成熟。

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