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[缺血状态及再灌注期间心肌损伤的机制——选定的分子及临床方面]

[Mechanism of myocardial injury during ischemic conditions and reperfusion--selected molecular and clinical aspects].

作者信息

Waleriańczyk M

机构信息

I Oddziału Chorób Wewnetrznych Szpitala Czerniakowskiego w Warszawie.

出版信息

Pol Tyg Lek. 1993;48(31-33):703-6.

PMID:7971495
Abstract

First, the author discusses phenomena seen in the myocardium during heart ischemia, and depicts dangerous period of so-called reperfusion in the paralysed area. A significance of free oxygen radicals and their origin with particular reference to their effects during reperfusion stage are emphasised. A possibility to use antioxidant agents to decrease a risk of clinical symptoms produced by reperfusion is also discussed.

摘要

首先,作者讨论了心脏缺血时心肌中出现的现象,并描述了麻痹区域所谓再灌注的危险时期。强调了游离氧自由基的重要性及其来源,特别提及它们在再灌注阶段的作用。还讨论了使用抗氧化剂降低再灌注产生临床症状风险的可能性。

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