Faller G, Hensen J, Thierauf P, Kirchner T
Pathologisches Institut, Universität Erlangen-Nürnberg.
Pathologe. 1994 Aug;15(4):242-5. doi: 10.1007/s002920050052.
A 56 year old mentally disabled woman of short stature was admitted to our hospital because of severe chest pain and dyspnoea. An extended myocardial infarction in the anterior wall was clinically found and confirmed by autopsy. On admission cretinism with massive myxedema was diagnosed, which was confirmed by subsequent laboratory findings. Only at the base of the tongue thyroid tissue 3 mm in diameter was found. In the anterior lobe of the pituitary gland areas with nodular hyperplasia and microadenomas of TSH-producing cells were detected. Thyrotroph adenomas in long standing hypothyroidism are rare. There are only few reports on congenital hypothyroidism as primary underlying disease.
一名56岁身材矮小的智障女性因严重胸痛和呼吸困难入住我院。临床上发现前壁广泛心肌梗死，并经尸检证实。入院时诊断为呆小症伴大量黏液性水肿，随后的实验室检查结果证实了这一诊断。仅在舌根处发现直径3毫米的甲状腺组织。在垂体前叶检测到促甲状腺激素分泌细胞的结节性增生和微腺瘤区域。长期甲状腺功能减退症中的促甲状腺激素腺瘤很少见。关于先天性甲状腺功能减退症作为原发性基础疾病的报道很少。
