Thurfjell E L, Lindgren J A
Department of Diagnostic Radiology, Akademiska sjukhuset, Uppsala, Sweden.
Radiology. 1994 Nov;193(2):351-7. doi: 10.1148/radiology.193.2.7972742.
To evaluate the results of a population-based mammography screening program in Uppsala County, Sweden, and to compare the findings with those of the randomized Swedish studies.
There were 43,074 women (aged 40-69 years) who were invited to the first screening round. Women aged 40-54 years were examined with two-view mammography, whereas women aged 55-69 years were examined with one-view mammography. During the second screening round, two-view mammography was used to screen dense breasts.
The attendance rate was 87% in the first screening round and 78% in the second screening round. The recall rate for further examination was 4.6% in the first round and 5.7% in the second round. On average, five cancers were found per 1,000 women examined in both screening rounds. The rate of advanced breast cancers of stage II or higher decreased statistically significantly from 0.16% in the first screening round to 0.08% in the second screening round (P = .007).
The results of the Swedish two-county study can be duplicated in clinical practice.
评估瑞典乌普萨拉郡基于人群的乳腺钼靶筛查项目的结果,并将结果与瑞典的随机研究结果进行比较。
43074名年龄在40 - 69岁之间的女性被邀请参加第一轮筛查。40 - 54岁的女性接受双视角乳腺钼靶检查,而55 - 69岁的女性接受单视角乳腺钼靶检查。在第二轮筛查中,双视角乳腺钼靶用于筛查致密型乳房。
第一轮筛查的参与率为87%,第二轮筛查为78%。第一轮进一步检查的召回率为4.6%,第二轮为5.7%。两轮筛查中,每1000名接受检查的女性平均发现5例癌症。II期或更高分期的晚期乳腺癌发生率从第一轮筛查的0.16%显著下降至第二轮筛查的0.08%(P = 0.007)。
瑞典两郡研究的结果在临床实践中可以复现。