Nuñoz Villa A, Hurtado T, García Miguel P, González M C, Fernández P, Petrement C, Claver M
An Esp Pediatr. 1976 Nov;9(8):72-81.
Eight cases of Ewing's tumor are reported. Four cases (50%) were localized forms at diagnosis and the remaining presented metastasis. The localized forms were treated with a combination of irradiation at dose of 4,500-5,000 rads and chemotherapy with vincristine and cyclophosphamide during two years. Three of these patients (75%) are alive and free of disease for more than two years. In the metastatic forms the treatment used was radiotherapy and diverse chemotherapy combinations with palliative intention. Bibliography related with this subject is reviewed and new chemotherapeutic combinations are discussed, the superiority of any treatment being not yet established.
报告了8例尤因肉瘤病例。4例(50%)在诊断时为局限性病变,其余病例有转移。局限性病变采用4500 - 5000拉德剂量的放疗联合长春新碱和环磷酰胺化疗,为期两年。其中3例患者(75%)存活且无病超过两年。对于转移性病变,采用的治疗方法是姑息性放疗和多种化疗联合方案。对与该主题相关的文献进行了综述,并讨论了新的化疗联合方案,目前尚未确定任何一种治疗方法的优越性。