Hoffmann R
Medizinische Klinik, Fachbereich Gastroenterologie, Städtische Krankenanstalten Esslingen.
Praxis (Bern 1994). 1994 Oct 18;83(42):1186-9.
For control of activity of inflammatory bowel diseases, clinical signs and acute-phase proteins are of higher value compared to endoscopy; however this method is necessary for supervision of patients with ulcerative colitis for detection of malignancies. In patients with longstanding and extensive ulcerative colitis, a consequent supervision permits to prevent cancer development markedly. New aminosalicylates are effective in preventing relapse in ulcerative colitis and perhaps in Crohn's disease. Deficiency in vitamins and minerals has to be recognized and balanced. Patients suffering from Crohn's disease should quit smoking because nicotine is worsening the course of the disease.
对于炎症性肠病活动的控制,与内镜检查相比,临床体征和急性期蛋白具有更高的价值;然而,这种方法对于溃疡性结肠炎患者监测恶性肿瘤的发生是必要的。对于长期患有广泛性溃疡性结肠炎的患者,持续的监测可显著预防癌症的发生。新型氨基水杨酸类药物在预防溃疡性结肠炎复发方面有效,可能对克罗恩病也有效。必须认识到并平衡维生素和矿物质的缺乏。患有克罗恩病的患者应该戒烟,因为尼古丁会使病情恶化。