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慢性炎症性肠病是癌前病变吗?(作者译)

[Are chronic inflammatory bowel diseases precancerous conditions?(author's transl)].

作者信息

Fahrländer H

出版信息

Leber Magen Darm. 1975 Dec;5(6):272-4.

PMID:1228362
Abstract

Cancer risk in patients with ulcerative colitis is higher than in patients with Crohn's disease, the reason for this difference being unknown. In ulcerative colitis the risk of malignancy justifies a prophylactic colectomy when the disease begins in childhood or in adolescence involving the total colon and lasting for more than 10 years. In Crohn's disease malignant tumors have been described in 43 cases of terminal ileitis and in 32 cases of granulomatous colitis. The cancer risk is low and does not justify a prophylactic colectomy.

摘要

溃疡性结肠炎患者的癌症风险高于克罗恩病患者,这种差异的原因尚不清楚。在溃疡性结肠炎中,当疾病始于儿童期或青春期,累及整个结肠且持续超过10年时,恶性肿瘤风险使得预防性结肠切除术成为必要。在克罗恩病中,已在43例末段回肠炎和32例肉芽肿性结肠炎患者中发现了恶性肿瘤。癌症风险较低,无需进行预防性结肠切除术。

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