Nargund V H, Barker I K, Coombs L, Flannigan G M, Stewart P A, Crawford S M
Cancer Medicine Research Unit, University of Bradford, West Yorkshire, UK.
Urol Res. 1994;22(2):75-7. doi: 10.1007/BF00310995.
The growth patterns of established cell lines from bladder transitional cell carcinoma (TCC) were compared with early passage cell lines. The growth of established cell line 5637 was uninhibited in both serum free (basal) and serum containing media. The early passage line (DR) grew only in serum containing medium. This confirms the unreliability of results from biological studies on established (continuous) cell lines.
将膀胱移行细胞癌(TCC)的已建细胞系的生长模式与早期传代细胞系进行了比较。已建细胞系5637在无血清(基础)培养基和含血清培养基中生长均不受抑制。早期传代细胞系(DR)仅在含血清培养基中生长。这证实了对已建(连续)细胞系进行生物学研究结果的不可靠性。