Ottenjann R
Z Gastroenterol. 1994 Jul;32(7):412-5.
The vast majority of gastrointestinal polyps are hyperplastic polyps or adenomas, their identification is possible bioptically. Adenomas are precancerous lesions, smaller ones with a diameter minor than 1 cm show invasive carcinoma in nearly 1%, in major polyps the percentage of invasive carcinoma will be 10% and more. Adenomas should therefore be removed with electrocautery snare (endoscopic polypectomy). Hamartomatous polyps (Peutz-Jeghers and juvenile polyps) are much less frequent, and mainly met with the Peutz-Jeghers syndrome (PJS) and familial juvenile polyposis (FJP). Hamartomas may bleed or induce obstruction or invagination. Adenomatous and malignant structures may be found within hamartomas, endoscopic polypectomy of these polyps is therefore mandatory. Mesenchymal (submucosal) polyps--leiomyoma, neurinoma--may only be identified by button-hole biopsy or after polypectomy; smaller submucosal polyps (up to 2 cm diameter) can be removed endoscopically, if strangulation is possible; the others should be removed during operation. Carcinoid tumors are rare within the upper and lower gastrointestinal tract, those with a diameter up to 1 cm should be removed by endoscopic polypectomy, larger ones have to be operated on.
绝大多数胃肠道息肉是增生性息肉或腺瘤,可通过活检进行鉴别。腺瘤是癌前病变,直径小于1 cm的小腺瘤发生浸润性癌的比例接近1%,较大息肉的浸润性癌比例可达10%或更高。因此,腺瘤应采用电凝圈套器切除(内镜下息肉切除术)。错构瘤性息肉(黑斑息肉病和幼年性息肉)较为少见,主要见于黑斑息肉综合征(PJS)和家族性幼年性息肉病(FJP)。错构瘤可能出血、导致梗阻或肠套叠。错构瘤内可能发现腺瘤性和恶性结构,因此必须对这些息肉进行内镜下息肉切除术。间叶性(黏膜下)息肉——平滑肌瘤、神经鞘瘤——只能通过咬取活检或息肉切除术后才能确诊;较小的黏膜下息肉(直径达2 cm),若有可能发生绞窄,可在内镜下切除;其他的则应在手术中切除。类癌肿瘤在上、下胃肠道中较为罕见,直径达1 cm的应通过内镜下息肉切除术切除,较大的则需手术治疗。