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[癫痫综合征合并感觉运动性失语及言语不能(Landau-Kleffner综合征)]

[The seizure syndrome combined with sensorimotor aphasia and alalia (the Landau-Kleffner syndrome)].

作者信息

Blagosklonova N K, Mastiukova E M

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1994;94(3):46-51.

PMID:7975989
Abstract

Electric brain activity and clinical status were studied in children with Landau-Kleffner syndrome. The paper covers 21 cases of the disease in patients aged from 2 years 11 months to 16 years in whom speech disorders and convulsive episodes varied in onset. A characteristic EEG pattern was recorded in the majority of the examinees. It comprised slow high-amplitude spike-and-wave complexes localized primarily in the temporal regions, more frequently on the left side. Clinically, the children belonged to 2 groups: epileptic aphasia and epileptic alalia patients. The latter had more significant EEG changes attributed to earlier onset of this disease. The data obtained showed the importance of combined clinical and EEG investigations in the diagnosis of Landau-Kleffner syndrome.

摘要

对患有Landau-Kleffner综合征的儿童进行了脑电活动和临床状况研究。本文涵盖了21例该疾病患者,年龄从2岁11个月至16岁,其言语障碍和惊厥发作的起病情况各不相同。大多数受检者记录到了特征性脑电图模式。它由主要位于颞区、更常见于左侧的缓慢高幅棘慢复合波组成。临床上,这些儿童分为两组:癫痫性失语和癫痫性哑症患者。后者脑电图变化更显著,这归因于该疾病起病较早。所获得的数据表明,临床和脑电图联合检查在Landau-Kleffner综合征诊断中的重要性。

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