Blazsó G, Gábor M
Institute of Pharmacodynamics, Albert Szent-Györgyi University Medical School, Hungary.
Acta Pharm Hung. 1994 Jul;64(4):123-4.
An experimental investigation was made of the influence of 0-(beta-hydroxyethyl)-rutin (HR) on the effect of indomethacin (1, 2 or 4 mg/kg i.p.) in inhibiting rat paw oedema. HR was given once daily during a 6-day pretreatment, with the final dose 90 minutes before the inflammatory reaction was induced. In the group of HR-pretreated rats which also received indomethacin in a dose of 2 or 4 mg/kg, the extent of the carrageenin-oedema was diminished significantly in comparison to that in experimental animals treated merely with indomethacin.
对0-(β-羟乙基)-芦丁（HR）对吲哚美辛（腹腔注射1、2或4mg/kg）抑制大鼠足爪水肿作用的影响进行了实验研究。在为期6天的预处理期间，每天给予一次HR，最后一剂在诱发炎症反应前90分钟给予。在预先用HR处理且也接受2或4mg/kg剂量吲哚美辛的大鼠组中，与仅用吲哚美辛处理的实验动物相比，角叉菜胶性水肿的程度显著降低。
