Poulsen L K, Bindslev-Jensen C, Rihoux J P
Laboratory of Medical Allergology, National University Hospital, Copenhagen, Denmark.
Agents Actions. 1994 Jun;41 Spec No:C134-5. doi: 10.1007/BF02007799.
For quantitative use of skin prick tests (SPTs), the circumference of the wheal and/or the flare is outlined by a pen, and transferred to a paper by adhesive tape. The biological response is considered proportional to this area. We have previously developed software, the SPT-scanner, for determination of SPT areas (5-500 mm2) by a hand-held scanner and a personal computer. This study is aimed at comparing the SPT-scanner with another semiautomated system, where the outline of the wheal is followed by a digitizer pen. Comparing 2080 SPT areas from a pharmacological study of cetirizine, the two systems correlated well (r = 0.980, p < 0.001), the digitizer generally giving larger areas than the SPT-scanner. Probably, the line is considered as a part of the wheal/flare in the digitizing system, whereas the scanner only detects areas within the circumference. In conclusion, the SPT scanner is objective and reproducible for rapid SPT area determination.
对于皮肤点刺试验（SPT）的定量应用，用钢笔勾勒出风团和/或红晕的周长，并用胶带转移到纸上。生物反应被认为与此面积成正比。我们之前开发了一款软件，即SPT扫描仪，用于通过手持扫描仪和个人计算机测定SPT面积（5 - 500平方毫米）。本研究旨在将SPT扫描仪与另一种半自动系统进行比较，该系统通过数字笔跟踪风团轮廓。在对西替利嗪进行的药理研究中比较了2080个SPT面积，两个系统相关性良好（r = 0.980，p < 0.001），数字笔测定的面积通常比SPT扫描仪测定的面积大。可能在数字化系统中，线条被视为风团/红晕的一部分，而扫描仪仅检测周长内的面积。总之，SPT扫描仪在快速测定SPT面积方面客观且可重复。
