Morrison J A, Payne G, Barton B A, Khoury P R, Crawford P
Division of Cardiology, Children's Hospital Medical Center, Cincinnati, Ohio.
Am J Public Health. 1994 Nov;84(11):1761-7. doi: 10.2105/ajph.84.11.1761.
This study sought to evaluate obesity as a potential explanatory factor for the increased relative risk for cardiovascular disease in Black compared with White women.
Familial associations for obesity and cardiovascular disease risk factors were assessed in 720 White and 580 Black mother-daughter pairs from the National Heart, Lung, and Blood Institute's Growth and Health Study by using Pearson's chi square, Spearman's correlations, and partial correlations.
Black girls and mothers were significantly heavier and had higher body mass indices than their White counterparts. In each racial group, significant, positive mother-daughter correlations existed for weight, body mass index, and triceps skinfolds, and for all cardiovascular disease risk factors. Obesity measures correlated positively with systolic blood pressure and triglycerides and inversely with high-density lipoprotein cholesterol in girls and mothers of both races. Correlations between mothers and daughters for exercise and ideal body shape were weak and did not explain obesity associations.
Intrafamilial associations of obesity, cardiovascular disease risk factors, and the obesity-cardiovascular disease risk factor relationship support the position that increased cardiovascular disease morbidity and mortality rates in Black women may be linked to excess obesity in Black women compared with White ones.
本研究旨在评估肥胖是否是黑人女性相较于白人女性心血管疾病相对风险增加的潜在解释因素。
利用Pearson卡方检验、Spearman相关性分析和偏相关性分析,对来自美国国立心肺血液研究所生长与健康研究中的720对白人母女和580对黑人母女的肥胖及心血管疾病风险因素的家族关联进行评估。
黑人女孩及其母亲比白人女孩及其母亲体重更重,身体质量指数更高。在每个种族群体中,体重、身体质量指数、肱三头肌皮褶厚度以及所有心血管疾病风险因素在母女之间均存在显著的正相关。在两个种族的女孩及其母亲中,肥胖指标与收缩压和甘油三酯呈正相关,与高密度脂蛋白胆固醇呈负相关。母亲与女儿在运动和理想体型方面的相关性较弱,无法解释肥胖之间的关联。
肥胖、心血管疾病风险因素的家族内关联以及肥胖与心血管疾病风险因素的关系支持以下观点:与白人女性相比,黑人女性心血管疾病发病率和死亡率增加可能与黑人女性过度肥胖有关。