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丙泊酚注射时的疼痛。硫喷妥钠预先给药的效果。

Pain during injection of propofol. The effect of prior administration of thiopentone.

作者信息

Lee T W, Loewenthal A E, Strachan J A, Todd B D

机构信息

Department of Anaesthesia and Intensive Care, Townsville General Hospital, Queensland, Australia.

出版信息

Anaesthesia. 1994 Sep;49(9):817-8.

PMID:7978145
Abstract

A controlled, double-blind study was performed to compare the prior administration of intravenous saline 4 ml (n = 36), lignocaine 20 mg (n = 36) or thiopentone 100 mg (n = 43) on the pain produced by intravenous injection of propofol. One hundred and fifteen ASA 1 or 2 patients scheduled for minor surgery were studied using a randomised, double-blind design. Thiopentone was more effective than lignocaine in reducing the incidence of propofol injection pain (p < 0.03).

摘要

进行了一项对照双盲研究,比较静脉注射4毫升生理盐水(n = 36)、20毫克利多卡因(n = 36)或100毫克硫喷妥钠(n = 43)对丙泊酚静脉注射所致疼痛的影响。采用随机双盲设计对115例计划进行小手术的ASA 1或2级患者进行了研究。硫喷妥钠在降低丙泊酚注射痛发生率方面比利多卡因更有效(p < 0.03)。

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