Lee T W, Loewenthal A E, Strachan J A, Todd B D
Department of Anaesthesia and Intensive Care, Townsville General Hospital, Queensland, Australia.
Anaesthesia. 1994 Sep;49(9):817-8.
A controlled, double-blind study was performed to compare the prior administration of intravenous saline 4 ml (n = 36), lignocaine 20 mg (n = 36) or thiopentone 100 mg (n = 43) on the pain produced by intravenous injection of propofol. One hundred and fifteen ASA 1 or 2 patients scheduled for minor surgery were studied using a randomised, double-blind design. Thiopentone was more effective than lignocaine in reducing the incidence of propofol injection pain (p < 0.03).
进行了一项对照双盲研究，比较静脉注射4毫升生理盐水（n = 36）、20毫克利多卡因（n = 36）或100毫克硫喷妥钠（n = 43）对丙泊酚静脉注射所致疼痛的影响。采用随机双盲设计对115例计划进行小手术的ASA 1或2级患者进行了研究。硫喷妥钠在降低丙泊酚注射痛发生率方面比利多卡因更有效（p < 0.03）。
