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侧卧位持续时间对脊髓麻醉期间丁卡因扩散的影响:一项前瞻性时间反应研究。

Influence of duration of lateral decubitus on the spread of hyperbaric tetracaine during spinal anesthesia: a prospective time-response study.

作者信息

Martin-Salvaj G, Van Gessel E, Forster A, Schweizer A, Iselin-Chaves I, Gamulin Z

机构信息

Department of Anesthesiology, University Hospital of Geneva, Switzerland.

出版信息

Anesth Analg. 1994 Dec;79(6):1107-12. doi: 10.1213/00000539-199412000-00014.

Abstract

Searching for a differential spinal block between dependent and nondependent sides, we evaluated a prospective randomized time-response study of the influence of the duration of lateral decubitus on the spread of hyperbaric local anesthetic solution during spinal anesthesia in 60 patients undergoing lower limb surgery. In a lateral position with the operated side dependent, all patients received 12 mg of lyophilized tetracaine with 0.2 mg epinephrine in 2.5 mL 10% dextrose and were randomized into four groups according to the duration of lateral decubitus after spinal injection: Group 0, patients immediately turned supine after spinal injection; Group 6, 6 min in lateral decubitus then supine; Group 12, 12 min in lateral decubitus then supine; Group 18, 18 min in lateral decubitus then supine. There was no difference in maximum sensory level between both sides in the same group nor between the four groups. In all four groups a comparable number of patients had a Grade 4 motor block on the dependent as well as on the nondependent side. A positive correlation found between duration of lateral decubitus and duration of sensory block on the dependent side suggested a preferential spread of hyperbaric local anesthetics. This differential spread was confirmed by the positive correlation between the duration of lateral decubitus and the difference in duration between dependent and nondependent sides of both sensory and motor blocks. However, because of the minimal differences between groups, we believe there is no reason to routinely maintain patients in the lateral position after performing spinal anesthesia.

摘要

为探寻脊柱阻滞在受压侧与非受压侧之间的差异,我们对60例接受下肢手术的患者进行了一项前瞻性随机时间反应研究,评估侧卧体位持续时间对脊麻期间高比重局部麻醉药溶液扩散的影响。所有患者在患侧在下的侧卧位接受12 mg冻干丁卡因与0.2 mg肾上腺素溶于2.5 mL 10%葡萄糖溶液中,根据脊麻注射后侧卧体位的持续时间随机分为四组:0组,脊麻注射后立即转为仰卧位;6组,侧卧6分钟后转为仰卧位;12组,侧卧12分钟后转为仰卧位;18组,侧卧18分钟后转为仰卧位。同一组两侧之间以及四组之间的最大感觉平面无差异。在所有四组中,受压侧和非受压侧出现4级运动阻滞的患者数量相当。侧卧体位持续时间与受压侧感觉阻滞持续时间之间呈正相关,提示高比重局部麻醉药有优先扩散现象。侧卧体位持续时间与感觉和运动阻滞的受压侧与非受压侧持续时间差异之间的正相关证实了这种差异扩散。然而,由于组间差异极小,我们认为在实施脊麻后没有理由常规让患者保持侧卧位。

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