Sass U, André J, Noël J C, Larsimont D, Olemans C, de Dobbeleer G, Wanet J, Ledoux M
Service de Dermato-Vénéréologie des Hôpitaux Universitaires Saint-Pierre et Brugmann, Bruxelles, Belgique.
Ann Dermatol Venereol. 1994;121(2):109-12.
Plexiform fibrohistiocytic tumour has been recently described by Enzinger and Zhang. This is a rare tumour with low grade malignancy which requires large excision. We report two cases, one occurring in a 58-year-old man, presenting a voluminous painless mass of 5 cm on his hand, the other occurring in a 9-year-old boy consulting for a nodule on the chest. On histological examination this dermal hypodermal tumour is characterized by a proliferation of histiocytic-like cells grouped in nodules, where they are associated with multinucleated osteoclastic-like cells and a proliferation of fibroblastic-like cells grouped in fascicles, anastomosing in a plexiform pattern. Immunohistochemistry and ultrastructural aspects are described. Differential diagnosis and histogenesis are discussed.
丛状纤维组织细胞瘤最近由恩津格和张描述。这是一种罕见的低度恶性肿瘤，需要广泛切除。我们报告两例病例，一例发生在一名58岁男性身上，手部出现一个5厘米的巨大无痛肿块，另一例发生在一名9岁男孩身上，因胸部有一个结节前来就诊。组织学检查显示，这种真皮和皮下肿瘤的特征是组织细胞样细胞呈结节状增生，在结节中它们与多核破骨细胞样细胞相关联，同时有成纤维细胞样细胞呈束状增生，并以丛状模式相互吻合。描述了免疫组织化学和超微结构方面的情况。讨论了鉴别诊断和组织发生。
