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校正精液果糖试验

Corrected seminal fructose test.

作者信息

Gonzales G F

机构信息

Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima.

出版信息

Arch Androl. 1994 Jul-Aug;33(1):17-22. doi: 10.3109/01485019408987798.

DOI:10.3109/01485019408987798
PMID:7979805
Abstract

Serum testosterone, seminal fructose, citric acid, and prolactin were measured in 33 men attending an infertility clinic. Seminal samples were assessed for leucocytes using the peroxidase stain technique and were grouped as leucocytospermics or not. Corrected fructose was calculated from actual fructose concentration. The objective of the study was to use the combined measurement of serum levels of testosterone and levels of corrected seminal fructose as a test to determine the presence or absence of an obstructive process by inflammation at the reproductive tract. Seminal fructose and corrected fructose were lower in subjects with leucocytospermia, whereas serum testosterone, seminal prolactin, and citric acid were not different between groups with and without leucocytospermia. In 61.5% of the samples with leucocytospermia were observed both low corrected seminal fructose and normal serum testosterone levels, indicating an obstructive process. Seminal prolactin levels in leucocytospermic subjects were more associated with citric acid concentration than with corrected fructose, suggesting that prolactin is also secreted by the prostate. In summary, the data demonstrated that when leucocytospermia, normal serum testosterone concentration, and low corrected seminal fructose level are present, an obstructive process of the seminal vesicles may be suspected.

摘要

对33名前往不孕不育诊所就诊的男性进行了血清睾酮、精液果糖、柠檬酸和催乳素的检测。采用过氧化物酶染色技术对精液样本进行白细胞评估,并将其分为白细胞精子症组和非白细胞精子症组。校正果糖由实际果糖浓度计算得出。本研究的目的是联合检测血清睾酮水平和校正精液果糖水平,以判断生殖道是否存在因炎症导致的梗阻性病变。白细胞精子症患者的精液果糖和校正果糖水平较低,而白细胞精子症组和非白细胞精子症组的血清睾酮、精液催乳素和柠檬酸水平无差异。在61.5%的白细胞精子症样本中,观察到校正精液果糖水平低且血清睾酮水平正常,提示存在梗阻性病变。白细胞精子症患者的精液催乳素水平与柠檬酸浓度的相关性高于与校正果糖的相关性,表明催乳素也由前列腺分泌。总之,数据表明,当存在白细胞精子症、血清睾酮浓度正常且校正精液果糖水平低时,可能怀疑精囊存在梗阻性病变。

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