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对不育男性的雄性生殖道雄激素活性进行检测。

Test for androgen activity at the male reproductive tract in infertile men.

作者信息

Gonzales G F

机构信息

Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima.

出版信息

Arch Androl. 1994 May-Jun;32(3):235-42. doi: 10.3109/01485019408987791.

DOI:10.3109/01485019408987791
PMID:8074579
Abstract

A study was conducted to determine the relationship between levels of serum testosterone and corrected seminal fructose levels in men under basal and post-clomiphene stimulation. A prospective controlled study was carried out in 19 selected men attending the andrology laboratory at the Instituto de Investigaciones de la Altura. These subjects were without any evidence of inflammation in the reproduction tract. The men received 100 mg clomiphene citrate daily for 5 days. Serum testosterone, seminal fructose, and corrected fructose levels were measured before and at the end of clomiphene citrate stimulation. Levels of serum T were related more with corrected seminal fructose than with seminal fructose concentrations under basal and stimulated conditions. Seventy-one percent of subjects with low levels of serum T had low levels of corrected seminal fructose, whereas only 28% of the same subjects had low levels of seminal fructose (uncorrected fructose). The results suggest that corrected seminal fructose may be used as a biological marker of androgen activity in the reproductive tract.

摘要

一项研究旨在确定基础状态下及克罗米芬刺激后男性血清睾酮水平与校正后精浆果糖水平之间的关系。对19名到身高研究所男科实验室就诊的男性进行了一项前瞻性对照研究。这些受试者生殖道无任何炎症迹象。男性每天服用100毫克枸橼酸克罗米芬,持续5天。在枸橼酸克罗米芬刺激前及刺激结束时测量血清睾酮、精浆果糖和校正果糖水平。在基础状态和刺激条件下,血清睾酮水平与校正后精浆果糖的相关性比与精浆果糖浓度的相关性更强。血清睾酮水平低的受试者中,71%校正后精浆果糖水平低,而同一受试者中只有28%精浆果糖(未校正果糖)水平低。结果表明,校正后精浆果糖可作为生殖道雄激素活性的生物学标志物。

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Test for androgen activity at the male reproductive tract in infertile men.对不育男性的雄性生殖道雄激素活性进行检测。
Arch Androl. 1994 May-Jun;32(3):235-42. doi: 10.3109/01485019408987791.
2
Use of clomiphene citrate in the treatment of men with high sperm chromatin stability.
Fertil Steril. 1998 Jun;69(6):1109-15. doi: 10.1016/s0015-0282(98)00090-9.
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Influence of low corrected seminal fructose levels on sperm chromatin stability in semen from men attending an infertility service.低校正精液果糖水平对就诊于不育门诊男性精液中精子染色质稳定性的影响。
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Is thyroid hormones evaluation of clinical value in the work-up of males of infertile couples?甲状腺激素评估在不育夫妇男性检查工作中具有临床价值吗?
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Corrected seminal fructose test.校正精液果糖试验
Arch Androl. 1994 Jul-Aug;33(1):17-22. doi: 10.3109/01485019408987798.
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Re: Gonzales, G. F. & Villena, A. (2001) True corrected seminal fructose level: a marker of the function of seminal vesicles in infertile men. International Journal of Andrology 24, 255-60.回复:冈萨雷斯,G.F. 及维列纳,A.(2001年)。真正校正后的精液果糖水平:不育男性精囊功能的一个标志物。《国际男科学杂志》24卷,第255 - 260页。
Int J Androl. 2002 Aug;25(4):253, author reply 254. doi: 10.1046/j.1365-2605.2002.00357.x.
10
The secretory activity of the seminal vesicles and its relationship to sperm motility: effects of infection in the male reproductive tract.
Int J Androl. 1989 Aug;12(4):286-94. doi: 10.1111/j.1365-2605.1989.tb01316.x.

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