Jung A C, Paauw D S
Department of Medicine, University of Washington, Seattle.
Arch Intern Med. 1994 Nov 14;154(21):2402-6.
Trimethoprim-sulfamethoxazole is an important medication for the treatment and prevention of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome. Use of this medication has been limited by the high frequency of adverse reactions that occur in patients with human immunodeficiency virus disease. This article reviews the incidence and spectrum of adverse reactions and options for continuing therapy with trimethoprim-sulfamethoxazole in human immunodeficiency virus-infected patients who have adverse reactions.
甲氧苄啶-磺胺甲恶唑是治疗和预防获得性免疫缺陷综合征患者卡氏肺孢子虫肺炎的重要药物。该药物的使用因人类免疫缺陷病毒病患者中不良反应的高发生率而受到限制。本文综述了不良反应的发生率和范围，以及在出现不良反应的人类免疫缺陷病毒感染患者中继续使用甲氧苄啶-磺胺甲恶唑进行治疗的选择。
