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Two nucleolar targeting signals present in the N-terminal part of Semliki Forest virus capsid protein.

作者信息

Favre D, Studer E, Michel M R

机构信息

Institute of Medical Microbiology, University of Berne, Switzerland.

出版信息

Arch Virol. 1994;137(1-2):149-55. doi: 10.1007/BF01311181.

DOI:10.1007/BF01311181
PMID:7979988
Abstract

Here we show that the capsid (C) protein of Semliki Forest virus (SFV) contains two nucleolar targeting signals (NOS) responsible for the karyophilic properties of this protein. When conjugated to the non-karyophilic carrier protein bovine serum albumin (BSA), the two synthetic nuclear localization sequences (NLS) of the C protein transferred with equal efficiency the carrier protein into the nucleolus of both higher and lower eukaryotic target cells.

摘要

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本文引用的文献

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Semliki Forest virus capsid protein expressed by a baculovirus recombinant.杆状病毒重组体表达的Semliki森林病毒衣壳蛋白。
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The capsid protein of Semliki Forest virus has clusters of basic amino acids and prolines in its amino-terminal region.Semliki森林病毒的衣壳蛋白在其氨基末端区域有碱性氨基酸簇和脯氨酸簇。
一种核仁蛋白MoRRP8是稻瘟病菌发育和致病性所必需的。
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