Jakob R
Institute for Applied Cell Culture, Munich, Germany.
J Med Microbiol. 1994 Jun;40(6):389-92. doi: 10.1099/00222615-40-6-389.
The nucleolar accumulation of Semliki Forest Virus (SFV) C protein was examined as a function of intact microtubules, intact microfilaments and accessible intermediate filaments. The cytoskeletal components do not seem to play a role in directing C protein to the nucleolus but nucleolar accumulation is energy-dependent and saturable. This suggests the involvement of some receptor- (or chaperon-) interaction.
研究了作为完整微管、完整微丝和可及中间丝功能的塞姆利基森林病毒(SFV)C蛋白的核仁积累情况。细胞骨架成分似乎在将C蛋白导向核仁的过程中不起作用,但核仁积累是能量依赖且可饱和的。这表明存在某些受体(或伴侣)相互作用。