Choi Y H, Furuse M, Okumura J, Denbow D M
Laboratory of Animal Nutrition, School of Agriculture, Nagoya University, Japan.
Brain Res. 1994 Aug 15;654(1):163-6. doi: 10.1016/0006-8993(94)91584-9.
To investigate the effect of nitric oxide (NO) on food intake in the chicken, L-NG-nitro-arginine methyl ester HCl (L-NNA), an inhibitor of NO synthase, was applied. When i.p. administered, L-NNA significantly inhibited the food intake of broiler chickens in a dose response manner. Food ingestion was also depressed by the i.c.v. injection of L-NNA in a dose response fashion. The effect of L-NNA was attenuated by i.c.v. administration of L-arginine. These results suggest that central NO may control feeding behavior in the chicken.
为研究一氧化氮（NO）对鸡采食量的影响，应用了NO合酶抑制剂盐酸L-NG-硝基精氨酸甲酯（L-NNA）。腹腔注射时，L-NNA以剂量反应方式显著抑制肉鸡的采食量。脑室内注射L-NNA也以剂量反应方式抑制食物摄取。L-精氨酸脑室内给药可减弱L-NNA的作用。这些结果表明，中枢NO可能控制鸡的摄食行为。
