以甲基-2,3,4,6-四-O-(4-甲氧基苄基)-1-硫代-β-D-吡喃半乳糖苷作为高效糖基供体合成含有α-Gal→β-Gal→GlcNAc序列的α-D-吡喃半乳糖基连接的寡糖。
Synthesis of alpha-D-galactopyranosyl-linked oligosaccharides containing the alpha-Gal-->beta-Gal-->GlcNAc sequence employing methyl-2,3,4,6-tetra-O-(4-methoxybenzyl)-1-thio-beta-D-galactopyranosid e as an efficient glycosyl donor.
作者信息
Reddy G V, Jain R K, Bhatti B S, Matta K L
机构信息
Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263.
出版信息
Carbohydr Res. 1994 Oct 3;263(1):67-77. doi: 10.1016/0008-6215(94)00153-7.
Synthesis of two trisaccharides and a tetrasaccharide, namely, alpha-Gal-(1-->3)-beta-Gal-(1-->3)-GlcNAc-beta-OBn (6), alpha-Gal-(1-->3)-beta-Gal-(1-->4)-GlcNAc-beta-OBn (9) and alpha-Gal-(1-->3)-beta-Gal-(1-->4)-GlcNAc-beta-(1-->6)-GalNAc- alpha-OBn (19) was accomplished through development and utilization of a key alpha-galactosyl donor, methyl 2,3,4,6-tetra-O-(4- methoxybenzyl)-1-thio-beta-D-galactopyranoside (1).
通过开发和利用关键的α-半乳糖基供体2,3,4,6-四-O-(4-甲氧基苄基)-1-硫代-β-D-吡喃半乳糖苷（1），实现了两种三糖和一种四糖的合成，即α-Gal-(1→3)-β-Gal-(1→3)-GlcNAc-β-OBn（6）、α-Gal-(1→3)-β-Gal-(1→4)-GlcNAc-β-OBn（9）和α-Gal-(1→3)-β-Gal-(1→4)-GlcNAc-β-(1→6)-GalNAc-α-OBn（19）。
Zotero 插件