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Synthesis of oligosaccharides containing beta-D-Gal-(1-->3)-O-(6-O-sulfo-beta-D-GlcNAc) as a terminal unit.

作者信息

Huang B G, Jain R K, Tabaczynski W A, Alderfer J L, Matta K L

机构信息

Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

出版信息

Carbohydr Res. 1998 Sep;311(3):165-9. doi: 10.1016/s0008-6215(98)00166-9.

DOI:10.1016/s0008-6215(98)00166-9
PMID:9825519
Abstract

The chemical synthesis of beta-D-Gal-(1-->3)-6-O-SO3Na-beta-D-GlcNAc-(1-->6)-alpha-D-Man-O-+ ++C6H4NO2 (1) and beta-D-Gal-(1-->3)-6-O-SO3Na-beta-D-GlcNAc-(1-->2)-alpha-D-Man-OMe (2) is reported using a key glycosyl donor, phenyl O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-(1-->3)-4,6-di-O- chloroacetyl-2-deoxy-2-phthalimido-1-thio-beta-D-glucopyranoside (3).

摘要

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引用本文的文献

1
Synthesis of Gal-beta-(1-->4)-GlcNac-beta-(1-->6)-[Gal-beta-(1-->3]-GalNAc-alpha- OBn oligosaccharides bearing O-methyl or O-sulfo groups at C-3 of the Gal residue: specific acceptors for Gal: 3-O-sulfotransferases.在半乳糖残基的C-3位带有O-甲基或O-磺基的Gal-β-(1→4)-GlcNac-β-(1→6)-[Gal-β-(1→3)]-GalNAc-α-OBn寡糖的合成:Gal:3-O-磺基转移酶的特异性受体。
Glycoconj J. 1998 Oct;15(10):951-9. doi: 10.1023/a:1006977607394.