Dieterle S, Mesrogli M, Triebler B, Wollenhaupt J, Nettelnbreker E, Schlösser H W
Abteilung Fertilität und Reproduktion, Medizinischen Hochschule Hannover.
Geburtshilfe Frauenheilkd. 1994 Aug;54(8):455-9. doi: 10.1055/s-2007-1022879.
A prospective study was performed to analyse the relationship between urogenital infections caused by Chlamydia trachomatis and occlusions of the fallopian tubes with histologically confirmed chronic salpingitis and salpingitis isthmica nodosa. 110 infertile patients were tested for C. trachomatis infection. 23 patients with tubal occlusions and histologically confirmed chronic salpingitis (group 1) and eight patients with salpingitis isthmica nodosa (group 2) were compared to 13 patients with tubal occlusions after tuboligation (group 3), and to 66 patients with patent fallopian tubes as demonstrated by laparoscopy or hysterosalpingography (group 4). The prevalence of infections of the endocervix or urethra and the presence of Chlamydia in urine was low in all four groups. However, in groups 1 and 2, the median Chlamydia IgG and IgA serum antibody titres were significantly higher (p < or = 0.0002) than in groups 3 and 4. This result illustrates the association between urogenital infections with Chlamydia and tubal occlusions with histologically documented chronic salpingitis and salpingitis isthmica nodosa.
开展了一项前瞻性研究，以分析沙眼衣原体引起的泌尿生殖系统感染与经组织学证实的慢性输卵管炎和结节性输卵管峡部炎导致的输卵管阻塞之间的关系。对110名不孕患者进行了沙眼衣原体感染检测。将23例伴有输卵管阻塞且经组织学证实为慢性输卵管炎的患者（第1组）和8例结节性输卵管峡部炎患者（第2组）与13例输卵管结扎术后出现输卵管阻塞的患者（第3组）以及66例经腹腔镜检查或子宫输卵管造影证实输卵管通畅的患者（第4组）进行比较。在所有四组中，宫颈或尿道感染的患病率以及尿液中衣原体的存在率都很低。然而，在第1组和第2组中，衣原体IgG和IgA血清抗体滴度中位数显著高于第3组和第4组（p≤0.0002）。这一结果说明了沙眼衣原体引起的泌尿生殖系统感染与经组织学记录的慢性输卵管炎和结节性输卵管峡部炎导致的输卵管阻塞之间的关联。
