Kaiser F E, Morley J E
Department of Medicine, St. Louis University School of Medicine, Missouri.
J Am Geriatr Soc. 1994 Dec;42(12):1291-4. doi: 10.1111/j.1532-5415.1994.tb06514.x.
Survey of the association of idiopathic CD4+ T cell lymphocytopenia in older persons with protein energy undernutrition and unusual infections/colonizations.
Retrospective chart analysis.
Five subjects aged 61 to 87 years, with unusual organisms and/or either marasmus or kwashiorkor, were noted to have absolute CD4+ and CD8+ T cell lymphocytopenia. All were HIV negative.
T cell lymphocytopenia may not be a uncommon finding in malnourished older persons, but additional studies to determine its prevalence need to be undertaken. Its role in disease and impact on therapeutic response needs to be further explored.
调查老年人特发性CD4+ T细胞淋巴细胞减少症与蛋白质能量营养不良及异常感染/定植之间的关联。
回顾性病历分析。
注意到5名年龄在61至87岁之间的受试者，伴有异常病原体和/或消瘦或夸希奥科病，存在绝对CD4+和CD8+ T细胞淋巴细胞减少。所有受试者均为HIV阴性。
T细胞淋巴细胞减少症在营养不良的老年人中可能并非罕见发现，但需要开展更多研究以确定其患病率。其在疾病中的作用及其对治疗反应的影响有待进一步探索。
