Heterogeneity in osteoporosis. Men versus women.

Although osteoporotic fractures have long been considered a special problem for postmenopausal women, osteoporosis is also an important clinical issue in men. The causes and clinical spectrum of osteoporosis is similar in men and women, but there are definite gender differences that reflect sexual differences in skeletal development, age-related bone loss, and secondary causes of metabolic bone disease.