Bazin N
Centre hospitalier général, Service de psychiatrie, Lagny-sur-Marne.
Rev Prat. 1994 Nov 1;44(17):2332-5.
Evaluation of cognitive disorders induced by treatment with psychotropic drugs is complex due to the involvement of several factors that can intervene in the pathogenesis and the evaluation of these disorders. Nevertheless, studies are numerous in the field, and we present the main reports. Most studies evaluating the influence of psychotropic drugs in healthy subjects indicate the existence of cognitive changes. On the contrary, aside from the effect of tranquillizers, and the sedative effect and/or the anticholinergic action of certain psychotropic drugs, in treated patients the individual responsibility of these drugs in cognitive disorders appears to have been often overestimated.
由于多种因素可干预精神药物所致认知障碍的发病机制及评估,因此对其进行评估较为复杂。然而,该领域的研究众多,我们在此呈现主要报告。大多数评估精神药物对健康受试者影响的研究表明存在认知变化。相反,除了镇静剂的作用以及某些精神药物的镇静作用和/或抗胆碱能作用外,在接受治疗的患者中,这些药物在认知障碍中的个体责任似乎常常被高估。