Frenkel' M A, Tupitsyn N N, Fleĭshman E V
Ter Arkh. 1994;66(7):7-10.
The paper presents the results of the retrospective study of blast cells from 377 patients with acute nonlymphoblastic leukemia (ANLL). Morphocytochemical, immunological, cytogenetic assessments and cloning in semisolid agar were employed. The authors specify blast characteristics with reference to ANLL variants according to the FAB classification, define diagnostic criteria for poorly differentiated myeloblastic (MO), erythroblastic (M6) and megakaryoblastic (M7) leukemia, hybrid variants.
本文介绍了对377例急性非淋巴细胞白血病(ANLL)患者原始细胞的回顾性研究结果。采用了形态细胞化学、免疫学、细胞遗传学评估以及半固体琼脂中的克隆技术。作者根据FAB分类法参照ANLL各变异型明确了原始细胞特征,定义了低分化髓细胞性(MO)、红细胞性(M6)和巨核细胞性(M7)白血病、混合变异型的诊断标准。