Kon'kova T A, Chudnovskaia M V, Golovanov S A
Urol Nefrol (Mosk). 1994 Jul-Aug(4):35-7.
Blood serum endotoxins were studied in patients with acute and chronic renal failure in order to correlate this spectrum with the treatment efficacy. Gel [correction of Liquid] chromatography tests of the serum samples were made in 106 patients on hemodialysis, hemodiafiltration and hemosorption. Hemodialysis was found to significantly reduce concentration of middle-mass molecular fraction (C, D, F with molecular mass from 300 to 2000 D). Hemodiafiltration produced the same effect, but more rapidly. A single procedure of hemosorption was able to improve the patients condition in the course of 2 postprocedure weeks. The authors attribute this effect to removal of the molecular fraction A which is highly toxic.
为了将这一情况与治疗效果相关联，对急性和慢性肾衰竭患者的血清内毒素进行了研究。对106例接受血液透析、血液透析滤过和血液吸附治疗的患者的血清样本进行了凝胶[将“液体”改为“凝胶”]色谱测试。发现血液透析能显著降低中分子质量组分（分子量为300至2000 D的C、D、F）的浓度。血液透析滤过也产生了同样的效果，但速度更快。单次血液吸附治疗能够在治疗后的两周内改善患者状况。作者将这种效果归因于去除了具有高毒性的分子组分A。
