Gorbunov V I, Gannushkina I V, Likhterman L B
Zh Vopr Neirokhir Im N N Burdenko. 1994 Jul-Sep(3):13-6.
The changes occurring in the immunity of 118 patients with focal brain injuries verified at surgery and during computed tomography were studied in relation to hemispheric lateralization. Patients with left-sided brain injuries showed more severe abnormalities of immunity and had a considerable lot of pyoinflammatory complications, including extracerebral ones. In patients with right-sided brain injuries, compensation of the changed immune responses occurred more rapidly, but intracranial pyoinflammatory complications took place more frequently. The magnitude and changes in immunity were found to depend upon the hemispheric lateralization of focal brain injuries, which characterizes that the brain regions play unequal role in the formation of an immune response. Differences become significant at week 3 at the peak of secondary immunodeficiency.
对118例经手术及计算机断层扫描证实为局灶性脑损伤患者的免疫变化进行了研究，探讨其与半球侧化的关系。左侧脑损伤患者的免疫异常更为严重，并有大量脓性炎症并发症，包括脑外并发症。右侧脑损伤患者免疫反应变化的代偿发生得更快，但颅内脓性炎症并发症发生得更频繁。发现免疫的程度和变化取决于局灶性脑损伤的半球侧化，这表明脑区在免疫反应形成中起不平等的作用。在继发性免疫缺陷高峰期的第3周，差异变得显著。
