Gorbunov V I
Zh Vopr Neirokhir Im N N Burdenko. 1992 Jan-Feb(1):27-9.
The dynamics of immunological values were studied in 350 patients with various types of craniocerebral trauma (CCT) in the acute period. It was established that immunological responses occur in all types of CCT. In mild CCT they are of a compensatory character. In severe trauma of the skull and brain the mechanisms of immunological protection are usually disrupted and secondary purulent complications and autoimmune processes develop. Under conditions of preliminary neurosensitization, the mechanisms of adaptation are disrupted even in mild traumas of the brain, autoimmune processes develop, which leads to a progredient course of CCT. Application of immunocorrective measures in disruption of adaptation processes improves the outcomes of CCT.
对350例急性期各种类型颅脑创伤（CCT）患者的免疫值动态变化进行了研究。结果表明，所有类型的CCT都会发生免疫反应。在轻度CCT中，它们具有代偿性。在严重的颅脑创伤中，免疫保护机制通常会受到破坏，继而发生化脓性并发症和自身免疫过程。在预先存在神经致敏的情况下，即使是轻度脑创伤，适应机制也会受到破坏，自身免疫过程会发展，从而导致CCT病情进展。在适应过程受到破坏时应用免疫纠正措施可改善CCT的治疗结果。
