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[一种用于测量白细胞杀念珠菌活性的简化微量方法(作者译)]

[A simplified micromethod for the measurement of leukocyte candidacidal activity (author's transl)].

作者信息

Laurenti F, Battaglia M, Lendvai D, Midulla M, Rezza E

出版信息

Ann Sclavo. 1976 Jul-Aug;18(4):574-84.

PMID:798556
Abstract

A technicall simple micromethod for the assessment of leukocyte candidacidal activity is described. It is based on the alterations in Giemsa staining characteristics which Candida albicans cells develop when ingested by glass-adhering phagocytes. This method, which requires small quantities of whole blood and produces reliable results, may be of promising clinical usefulness for detecting primary and secondary phagocyte candidacidal defects in patients with chronic or recurrent localized and systemic candidiasis.

摘要

本文描述了一种技术上简单的微量方法,用于评估白细胞的杀念珠菌活性。该方法基于白色念珠菌细胞被玻璃黏附吞噬细胞吞噬后吉姆萨染色特征的改变。这种方法所需全血量少且结果可靠,对于检测慢性或复发性局部及全身性念珠菌病患者的原发性和继发性吞噬细胞杀念珠菌缺陷可能具有良好的临床应用前景。

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