Flynn F W, Ramos R
Department of Psychology, University of Wyoming.
Behav Neurosci. 1994 Aug;108(4):780-8. doi: 10.1037//0735-7044.108.4.780.
The researchers performed experiments to evaluate whether the effects of bombesin are selective for the satiation of ingestive behaviors related to energy balance or if ingestive behaviors associated with sodium balance are also suppressed by bombesin. Injections of 4 and 8 micrograms/kg bombesin reliably reduced need-free and sodium deficiency-induced NaCl intake in male rats. The effects of bombesin on the sodium-deficiency-induced change in taste reactivity was assessed. Injections of 4 micrograms/kg and 8 micrograms/kg bombesin had no effect on the sodium deficiency-induced shift in taste reactivity. These data indicate that bombesin suppresses NaCl intake and that bombesin does not appear to interact with gustatory sensibility in exerting its behavior-controlling action.
研究人员进行了实验，以评估蛙皮素的作用是否对与能量平衡相关的摄食行为的饱腹感具有选择性，或者与钠平衡相关的摄食行为是否也会被蛙皮素抑制。注射4微克/千克和8微克/千克的蛙皮素能可靠地减少雄性大鼠无需求和缺钠诱导的氯化钠摄入量。评估了蛙皮素对缺钠诱导的味觉反应变化的影响。注射4微克/千克和8微克/千克的蛙皮素对缺钠诱导的味觉反应变化没有影响。这些数据表明，蛙皮素会抑制氯化钠的摄入，并且蛙皮素在发挥其行为控制作用时似乎不与味觉敏感性相互作用。
