Vgontzas A N, Bixler E O, Kales A, Manfredi R L, Tyson K
Sleep Research & Treatment Center, Pennsylvania State University College of Medicine, Hershey 17033.
Int J Neurosci. 1994 Jul;77(1-2):11-21. doi: 10.3109/00207459408986015.
The sensitivity, specificity, and positive predictive value of two proposed sleep laboratory criteria for the diagnosis of insomnia were evaluated in 375 adults with a primary complaint of insomnia and 150 noninsomniac controls. The two criteria used results in either low sensitivity and moderately strong specificity or high sensitivity and low specificity and, accordingly, in both cases weak positive predictive values (diagnostic accuracy), both for one night and multiple nights of recordings. Further, an empirically optimized criterion also resulted in an unsatisfactory diagnostic accuracy. Finally, the optimized MMPI criteria were superior to optimized sleep criteria in differentiating insomniacs from controls. In conclusion, sleep laboratory recordings provide little relevant information for confirming or excluding the presence of insomnia.
在375名以失眠为主诉的成年人和150名非失眠对照组中，对两种用于诊断失眠的睡眠实验室标准的敏感性、特异性和阳性预测值进行了评估。这两种标准的结果要么是低敏感性和中等强度的特异性，要么是高敏感性和低特异性，因此，在这两种情况下，无论是一晚还是多晚的记录，阳性预测值（诊断准确性）都很弱。此外，一个经验优化的标准也导致了不令人满意的诊断准确性。最后，在区分失眠者和对照组方面，优化后的明尼苏达多相人格调查表（MMPI）标准优于优化后的睡眠标准。总之，睡眠实验室记录对于确认或排除失眠的存在几乎没有提供相关信息。
