环丙沙星与芬布芬之间不存在药代动力学相互作用。
Lack of a pharmacokinetic interaction between ciprofloxacin and fenbufen.
作者信息
Kamali F
机构信息
Wolfson Unit of Clinical Pharmacology, University of Newcastle, U.K.
出版信息
J Clin Pharm Ther. 1994 Aug;19(4):257-9. doi: 10.1111/j.1365-2710.1994.tb00683.x.
Abstract
The possible effects of a three day pretreatment with fenbufen on the pharmacokinetics of a single oral (500 mg) dose of ciprofloxacin were evaluated in a randomized crossover study in a group of eight healthy male volunteers. Fenbufen pretreatment was shown to have no significant effect on ciprofloxacin pharmacokinetics.
摘要
在一项针对8名健康男性志愿者的随机交叉研究中，评估了芬布芬进行为期三天的预处理对单次口服（500毫克）环丙沙星药代动力学的可能影响。结果显示，芬布芬预处理对环丙沙星的药代动力学没有显著影响。
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