甲氨蝶呤治疗间质部妊娠：1例失败病例报告。
Treatment of interstitial pregnancy with methotrexate: report of an unsuccessful case.
作者信息
Voigt R R, van der Veen F, Karsdorp V H, Hogerzeil H V, Ketting B W
机构信息
Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, The Netherlands.
出版信息
Hum Reprod. 1994 Aug;9(8):1576-9. doi: 10.1093/oxfordjournals.humrep.a138752.
Abstract
Until now, the traditional management of interstitial pregnancy has been surgical. Lately, we have advocated conservative treatment with methotrexate as an option for infertility patients. This is the first publication of a rupture with abundant intra-abdominal bleeding during systemic treatment with methotrexate of a patient with an interstitial pregnancy. Signs of therapy failure are discussed.
摘要
直到现在，间质部妊娠的传统治疗方法一直是手术治疗。最近，我们提倡对不孕患者采用甲氨蝶呤进行保守治疗。本文首次报道了1例间质部妊娠患者在甲氨蝶呤全身治疗期间发生破裂并伴有大量腹腔内出血的病例。文中还讨论了治疗失败的征象。
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