Hoencamp E, Haffmans P M, Duivenvoorden H, Knegtering H, Dijken W A
Out-patient Department, Psychiatric Centre Bloemendaal, The Hague, The Netherlands.
J Affect Disord. 1994 Aug;31(4):235-46. doi: 10.1016/0165-0327(94)90099-x.
The predictive value of eight domains or sets of variables including sociodemographic aspects, premorbid history, symptomatology, personality, social and diagnostic data are evaluated in depressed outpatients with a Hamilton Rating Scale for Depression (HRSD) score of at least 14. Patients were treated using a three-phase sequential treatment strategy. Of the 119 patients, 88 completed the trial. The HRSD-score at the end of phases I, II or III was used as an outcome measure. Patients with an initially high HRSD-score and an obsessive-compulsive personality had a greater chance of recovery, while patients with somatization and a passive-aggressive personality had less of a chance of recovery. Variables involving psychiatric history, premorbid history or symptomatology of the depression, were not significantly related to outcome. The endogenous/non-endogenous distinction was not a predictor of response.
对包括社会人口学特征、病前史、症状学、人格、社会和诊断数据在内的八个领域或变量集的预测价值进行了评估，研究对象为汉密尔顿抑郁量表（HRSD）评分至少为14分的门诊抑郁症患者。患者采用三阶段序贯治疗策略进行治疗。119例患者中，88例完成了试验。将I期、II期或III期结束时的HRSD评分用作结局指标。初始HRSD评分高且具有强迫性人格的患者康复机会更大，而有躯体化症状且具有被动攻击型人格的患者康复机会较小。涉及精神病史、病前史或抑郁症症状学的变量与结局无显著相关性。内源性/非内源性的区分不是反应的预测指标。
