Gamba P G, Messineo A, Antoniello L M, Boccato P, Blandamura S, Cecchetto G, Dall'Igna P, Guglielmi M
Pediatric Surgical Department, University of Padua, Italy.
Med Pediatr Oncol. 1995 Feb;24(2):97-9. doi: 10.1002/mpo.2950240207.
Fine-needle aspiration cytology (FNAC) is now considered a useful tool in the evaluation of adult patients with mass lesions. We reviewed the experience with FNAC in our Paediatric Surgical Department. One hundred and eleven FNACs were performed in children with a superficial mass and no definite diagnosis. All the exams were done by the same physician using a fine needle and no anesthesia. We routinely used May-Grüwald-Giemsa and Papanicolaou staining. Patients age ranged from 20 days to 17 years, with a mean age of 6.5 years. A clinically benign pathology was cytologically confirmed in 90 cases (81%). All children did well at follow-up. Malignancy was diagnosed in eight cases (7.2%) and in all was confirmed with a surgical biopsy. In nine children (8.1%) the specimen was considered insufficient for definite diagnosis. In four cases (3.6%) the pathologist diagnosed a possible malignancy that was excluded at surgical biopsy. The sensitivity was 100% and the specificity was 96%. Our experience confirms that FNAC is a fast, cheap, simple, and accurate diagnostic method and should be used for screening in all children with doubtful superficial masses.
细针穿刺细胞学检查（FNAC）现在被认为是评估患有肿块病变的成年患者的一种有用工具。我们回顾了我们儿科外科进行FNAC的经验。对111例有浅表肿块且未明确诊断的儿童进行了FNAC检查。所有检查均由同一位医生使用细针进行，且未使用麻醉。我们常规使用May-Grüwald-Giemsa和巴氏染色。患者年龄从20天至17岁不等，平均年龄为6.5岁。90例（81%）病例在细胞学上证实为临床良性病理。所有儿童在随访中情况良好。8例（7.2%）诊断为恶性肿瘤，均经手术活检证实。9例（8.1%）患儿的标本被认为不足以进行明确诊断。4例（3.6%）病例病理学家诊断为可能的恶性肿瘤，但在手术活检时被排除。敏感性为100%，特异性为96%。我们的经验证实，FNAC是一种快速、廉价、简单且准确的诊断方法，应用于所有有可疑浅表肿块儿童的筛查。
