Orford J E, Gollow I, Brennan B, Hallam L
Division of Surgery, Princess Margaret Hospital for Children, Perth, Western Australia.
Aust N Z J Surg. 1997 Nov;67(11):785-8. doi: 10.1111/j.1445-2197.1997.tb04580.x.
Fine needle biopsy (FNB) in children has been slow to gain acceptance compared with the use of the technique in adults where it is regarded as standard clinical practice in screening significant lymphadenopathy and suspicious masses. We report our early experience with FNB in the paediatric population.
Fifty-two biopsies were performed between June 1991 and June 1993. The age of the children ranged from 6 months to 14 years (median 2 years, mean 5 years).
A definite diagnosis on cytology alone was obtained in 67%. The pathologist was certain of malignant or nonmalignant potential in 79% (67% benign and 12% malignant) and unsure in 21% (17% benign and 4% malignant). There were no false positive or false negative diagnoses of malignancy. Surgical excision or biopsy was performed in 33%. Fine needle biopsy assisted in planning surgery in 12%. Surgery was necessary for a definite diagnosis in 21% and FNB assisted 42% of the patients to avoid surgery altogether.
Fine needle biopsy is simple, minimally invasive and useful in the evaluation of children with suspicious lymph nodes and masses.
与在成人中使用细针穿刺活检（FNB）相比，该技术在儿童中的接受程度增长缓慢。在成人中，FNB被视为筛查重大淋巴结病和可疑肿块的标准临床实践。我们报告了我们在儿科人群中使用FNB的早期经验。
1991年6月至1993年6月期间进行了52次活检。儿童年龄从6个月至14岁不等（中位数2岁，平均5岁）。
仅通过细胞学检查就明确诊断的比例为67%。病理学家确定具有恶性或非恶性可能性的比例为79%（67%为良性，12%为恶性），不确定的比例为21%（17%为良性，4%为恶性）。没有恶性肿瘤的假阳性或假阴性诊断。33%的患者进行了手术切除或活检。FNB辅助手术规划的比例为12%。21%的患者需要手术以明确诊断，FNB帮助42%的患者完全避免了手术。
细针穿刺活检简单、微创，对评估有可疑淋巴结和肿块的儿童有用。
