Roa J C, Chuaqui R, Le Cerf P
Departamento de Anatomía Patológica, Escuela de Medicina, Pontificia Universidad Católica de Chile.
Rev Chil Obstet Ginecol. 1993;58(5):388-92.
The frequency of Hendrickson's and Kurman's criteria for the diagnosis of endometrial carcinoma was analyzed in 25 cases of endometrial curettings in which the diagnosis of atypical hyperplasia was made. All cases had subsequent hysterectomies not showing carcinoma. Hendrickson's cytologic elements were found in 88% of the cases and architectural elements in 84% of the cases. Kurman's architectural elements were not found. In only one case stromal desmoplasia was present; 3 cases (12%) showed small cribes, all of them in tiny foci less than 0.5 mm. Small glands were present in 76% of the cases. Hendrickson's cytological and architectural criteria are not specific for carcinoma; they are frequently found in atypical hyperplasias. Kurman's criteria are absent in endometrial hyperplasias. Most cases of endometrial atypical hyperplasia do not show small cribes; when the latter are present, they are only focally found and measure less than 0.5 mm.
对25例诊断为非典型增生的子宫内膜刮除术病例分析了亨德里克森(Hendrickson)和库尔曼(Kurman)诊断子宫内膜癌标准的出现频率。所有病例随后均进行了子宫切除术,结果未发现癌变。在88%的病例中发现了亨德里克森的细胞学特征,在84%的病例中发现了其结构特征。未发现库尔曼的结构特征。仅1例存在间质纤维组织增生;3例(12%)显示有小筛状结构,均存在于小于0.5毫米的微小病灶中。76%的病例中有小腺体。亨德里克森的细胞学和结构标准并非癌所特有;它们在非典型增生中经常出现。子宫内膜增生中不存在库尔曼的标准。大多数子宫内膜非典型增生病例未显示小筛状结构;当出现小筛状结构时,仅局灶性存在且大小小于0.5毫米。