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膳食纤维对大鼠化学诱导肠道肿瘤的保护作用。

Protective effect of dietary fibre against chemically induced bowel tumours in rats.

作者信息

Fleiszer D, Murray D, MacFarlane J, Brown R A

出版信息

Lancet. 1978 Sep 9;2(8089):552-3. doi: 10.1016/s0140-6736(78)92885-4.

DOI:10.1016/s0140-6736(78)92885-4
PMID:79919
Abstract

101 rats were fed one of four diets containing graded amounts of dietary fibre. Subcutaeous dimethylhydrazine (D.M.H.) was given to half the rats in each of the diet groups. Stool mass was found to be directly related to the amount of dietary fibre consumed, and the incidence of D.M.H.-induced colon carcinoma was reduced as dietary fibre increased.

摘要

101只大鼠被喂食含有不同膳食纤维量的四种饮食之一。每个饮食组中的一半大鼠皮下注射二甲基肼(D.M.H.)。发现粪便量与膳食纤维摄入量直接相关,并且随着膳食纤维增加,D.M.H.诱导的结肠癌发病率降低。

相似文献

1
Protective effect of dietary fibre against chemically induced bowel tumours in rats.膳食纤维对大鼠化学诱导肠道肿瘤的保护作用。
Lancet. 1978 Sep 9;2(8089):552-3. doi: 10.1016/s0140-6736(78)92885-4.
2
Failure of bran to protect against experimental colon cancer in rats.
Lancet. 1978 Dec 16;2(8103):1278-80. doi: 10.1016/s0140-6736(78)92041-x.
3
Effects of diet on chemically induced bowel cancer.饮食对化学诱导性肠癌的影响。
Can J Surg. 1980 Jan;23(1):67-73.
4
Reduction of DMH-induced colon tumors in rats fed psyllium husk or cellulose.喂食车前草壳或纤维素的大鼠中,DMH诱导的结肠肿瘤数量减少。
Nutr Cancer. 1987;10(3):129-36. doi: 10.1080/01635588709513949.
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Dietary fibre and experimental colon cancer.膳食纤维与实验性结肠癌
Lancet. 1978 Oct 7;2(8093):784-5. doi: 10.1016/s0140-6736(78)92667-3.
6
A double-blind study on the effects of differing purified cellulose and pectin fiber diets on 1,2-dimethylhydrazine-induced rat colonic neoplasia.一项关于不同纯化纤维素和果胶纤维饮食对1,2-二甲基肼诱导的大鼠结肠肿瘤形成影响的双盲研究。
Cancer Res. 1980 Aug;40(8 Pt 1):2661-5.
7
The effect of the fiber components cellulose and lignin on experimental colon neoplasia.纤维成分纤维素和木质素对实验性结肠肿瘤形成的影响。
J Surg Oncol. 1993 Feb;52(2):77-82. doi: 10.1002/jso.2930520204.
8
Colonic protection from dimethylhydrazine by a high fiber diet.
Surg Gynecol Obstet. 1978 Oct;147(4):503-6.
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Dietary fibre and chemically induced bowel tumours.膳食纤维与化学诱导的肠道肿瘤
Lancet. 1978 Dec 9;2(8102):1252. doi: 10.1016/s0140-6736(78)92121-9.
10
Bran and experimental colon cancer.
Lancet. 1979 Jan;1(8107):108.

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Dietary fibre and colonic neoplasia.膳食纤维与结肠肿瘤
Can Med Assoc J. 1979 Aug 4;121(3):291-6.
9
Dietary fiber.膳食纤维
West J Med. 1979 Apr;130(4):375-6.
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Metabolic effects of dietary fiber.膳食纤维的代谢效应。
West J Med. 1979 Feb;130(2):123-7.