膳食纤维对大鼠化学诱导肠道肿瘤的保护作用。
Protective effect of dietary fibre against chemically induced bowel tumours in rats.
作者信息
Fleiszer D, Murray D, MacFarlane J, Brown R A
出版信息
Lancet. 1978 Sep 9;2(8089):552-3. doi: 10.1016/s0140-6736(78)92885-4.
PMID:79919
Abstract
101 rats were fed one of four diets containing graded amounts of dietary fibre. Subcutaeous dimethylhydrazine (D.M.H.) was given to half the rats in each of the diet groups. Stool mass was found to be directly related to the amount of dietary fibre consumed, and the incidence of D.M.H.-induced colon carcinoma was reduced as dietary fibre increased.
摘要
101只大鼠被喂食含有不同膳食纤维量的四种饮食之一。每个饮食组中的一半大鼠皮下注射二甲基肼（D.M.H.）。发现粪便量与膳食纤维摄入量直接相关，并且随着膳食纤维增加，D.M.H.诱导的结肠癌发病率降低。
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