Zhang S, Cheng F, Webber R
Institute of Parasitic Diseases, Hubei Academy of Medical Sciences, Wuhan, China.
Trans R Soc Trop Med Hyg. 1994 Sep-Oct;88(5):510-2. doi: 10.1016/0035-9203(94)90140-6.
This paper describes the epidemiology and control of human lymphatic filariasis in Hubei province, China from the 1950s to the 1990s. Brugia malayi, transmitted by Anopheles sinensis, and Wuchereria bancrofti, transmitted by Culex quinquefasciatus, were found in 69 of 78 counties and cities. The distribution of filaria species was distinct, with B. malayi endemic in the plains, mixed infections in hilly areas, and W. bancrofti in the mountains. Before 1979, the microfilaria rate (mfr) in some villages was as high as 30.69%. Since 1979, large scale control programmes have been carried out and 27,875,267 blood examinations have been made. Up to 1988, the mfr in all endemic villages decreased to below 1%. From 1989 to 1991 about 200,000 people had their blood examined yearly and few cases were detected. The continued use of mass blood examination for filariasis surveillance is not economic at such low levels of infection, and it is suggested that selective treatment of microfilaremic persons should be the main control measure at this stage.
本文描述了20世纪50年代至90年代中国湖北省人体淋巴丝虫病的流行病学及防治情况。在78个县（市）中的69个发现了由中华按蚊传播的马来布鲁线虫以及由致倦库蚊传播的班氏吴策线虫。丝虫种类的分布各异，马来布鲁线虫在平原地区为地方性流行，丘陵地区为混合感染，班氏吴策线虫则在山区流行。1979年前，一些村庄的微丝蚴率高达30.69%。自1979年以来，开展了大规模防治项目，共进行了27,875,267人次的血液检查。截至1988年，所有流行村庄的微丝蚴率均降至1%以下。1989年至1991年期间，每年约有20万人接受血液检查，仅发现少数病例。在感染率如此低的情况下，继续采用大规模血液检查进行丝虫病监测并不经济，建议现阶段以选择性治疗微丝蚴血症患者作为主要防治措施。
