Gaafar A, Fadl A, el Kadaro A Y, el Hassan M M, Kemp M, Ismail A I, Morgos S A, el Hassan A M
Centre for Medical Parasitology, University of Copenhagen, Denmark.
Trans R Soc Trop Med Hyg. 1994 Sep-Oct;88(5):552-4. doi: 10.1016/0035-9203(94)90158-9.
Sporotrichoid cutaneous leishmaniasis is due to dissemination of amastigotes via the lymphatics to the subcutaneous tissues. A comparison was made between the potential to disseminate by this route of 2 parasites of different zymodemes in Sudan and Saudi Arabia. In Sudan cutaneous leishmaniasis is caused by Leishmania major zymodeme LON-1, and in Saudi Arabia by L. major LON-4. Sporotrichoid leishmaniasis was significantly more common in Sudan, occurring in 23% of patients compared with 10% in Saudi Arabia. Lymph node involvement was slightly more prevalent in the Sudan. Clinical and pathological differences between subcutaneous nodules, particularly when they ulcerate, and multiple primary cutaneous lesions are described and treatment of localized and sporotrichoid leishmaniasis is discussed. The pathological features of the primary lesions in the Sudan and Saudi Arabia were similar.
孢子丝菌病样皮肤利什曼病是由于无鞭毛体通过淋巴管扩散至皮下组织所致。对苏丹和沙特阿拉伯两种不同酶株型的寄生虫通过该途径扩散的可能性进行了比较。在苏丹，皮肤利什曼病由硕大利什曼原虫酶株型LON-1引起，在沙特阿拉伯则由硕大利什曼原虫LON-4引起。孢子丝菌病样利什曼病在苏丹明显更为常见，23%的患者出现该病，而在沙特阿拉伯为10%。苏丹淋巴结受累略更为普遍。描述了皮下结节，特别是溃疡时与多发性原发性皮肤病变之间的临床和病理差异，并讨论了局限性和孢子丝菌病样利什曼病的治疗。苏丹和沙特阿拉伯原发性病变的病理特征相似。
