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[适度饮酒与缺血性心脏病风险降低。因果关系还是巧合?]

[Moderate alcohol consumption and reduced risk of ischemic heart disease. A causal connection or a coincidence?].

作者信息

Skovenborg E

机构信息

Brobjerg Centret, Egå.

出版信息

Ugeskr Laeger. 1994 Aug 29;156(35):4951-7.

PMID:7992425
Abstract

A negative association between light to moderate alcohol consumption and the risk of coronary heart disease has been documented in numerous ecological, case-control and cohort studies. The observed association is in the order of a 40-60% reduction in risk among light to moderate drinkers. The epidemiological findings are consistent, and several plausible biological mechanisms by which alcohol could reduce the risk of coronary heart disease add support to the hypothesis that the association is casual. The epidemiological evidence confirms the wellknown risk of adverse health effects of alcohol consumption above one to two drinks a day for women and one to three drinks a day for men.

摘要

大量的生态学、病例对照和队列研究都记录了轻度至中度饮酒与冠心病风险之间的负相关关系。在轻度至中度饮酒者中,观察到的关联是风险降低40%-60%。流行病学研究结果是一致的,酒精降低冠心病风险的几种合理生物学机制也支持了这种关联是因果关系的假设。流行病学证据证实了众所周知的风险,即女性每天饮酒超过1-2杯、男性每天饮酒超过1-3杯会对健康产生不良影响。

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