Rosencher N, Vassilieff V, Tallet F, Toulon P, Leoni J, Tomeno B, Conseiller C
Département d'Anesthésie-Réanimation Chirurgicale, Hôpital Cochin, Paris.
Ann Fr Anesth Reanim. 1994;13(3):318-25. doi: 10.1016/s0750-7658(94)80040-5.
Surgical wound blood which is ched through drains after total knee replacement surgery with a tourniquet may be returned to the patient using special collecting devices. This study aimed to compare two systems, Orth-Evac and Solcotrans Plus an to assess the safety of the reinfusion of non washed blood cells. It included 30 patients scheduled for total knee replacement surgery, free from tumoral or coagulation disease and allocated randomly in three groups of 10 each: the Orth-Evac group (OGr), the Solcotrans Plus group (SGr) and the Control group (CGr). The devices, not containing an anticoagulant, were connected to the deep suction drains in the operating room, after skin closure and before the tourniquet removal. The salvaged blood was reinfused in the subsequent six hours via a 40 microns filter. The volume of collected blood was measured and homologous blood was added as required, to maintain a hematocrit of 30%. A blood sample was obtained the day before surgery (D - 1), before reinfusion (D0), two hours later (D + 2h), one day later (D + 1), and from the collecting device before reinfusion. The statistical analysis used the Kruskal-Wallis test and Steel-Dwass procedure to confirm the difference between two groups. The three groups did not differ in age, weight, height and gender. The volume of salvaged and autotransfused blood was 925 +/- 156 mL in OGr and 605 +/- 178 mL in SGr respectively, transfusion of homologous blood was required in two patients of OGr, four of SGr and six of CGr. At D + 1, the hematocrit was comparable in all groups (OGr = 28%, SGr = 28.2% and CGr = 28.5%).(ABSTRACT TRUNCATED AT 250 WORDS)
全膝关节置换手术使用止血带后,经引流管引出的手术伤口血液可通过特殊收集装置回输给患者。本研究旨在比较Orth-Evac和Solcotrans Plus这两种系统,并评估未洗涤血细胞回输的安全性。研究纳入30例计划行全膝关节置换手术的患者,这些患者无肿瘤或凝血疾病,随机分为三组,每组10例:Orth-Evac组(O组)、Solcotrans Plus组(S组)和对照组(C组)。这些不含抗凝剂的装置在皮肤缝合后、止血带移除前,于手术室连接至深部吸引引流管。回收的血液在随后6小时内通过40微米过滤器回输。测量收集的血液量,并根据需要添加同源血,以维持血细胞比容为30%。在手术前一天(D - 1)、回输前(D0)、两小时后(D + 2小时)、一天后(D + 1)以及回输前从收集装置采集血样。统计分析采用Kruskal-Wallis检验和Steel-Dwass程序来确认两组之间的差异。三组在年龄、体重、身高和性别方面无差异。O组回收和自体回输的血液量分别为925±156毫升,S组为605±178毫升,O组有2例患者、S组有4例患者和C组有6例患者需要输注同源血。在D + 1时,所有组的血细胞比容相当(O组 = 28%,S组 = 28.2%,C组 = 28.5%)。(摘要截选至250字)