Contiero E, Chinello G E, Folin M
Department of Biology, University of Padua, Italy.
Anthropol Anz. 1994 Sep;52(3):221-30.
In the present study, total cholesterol, triglyceride, HDL-cholesterol and LDL-cholesterol concentrations were evaluated in 393 Italian male blood donors aged from 20 to 59 years and the association between these variables and ABO blood groups was examined. Through multiple linear regression we found that the variance in serum variable concentrations was significantly influenced by variance in the other serum variables, while lipid and lipoprotein levels were not significantly influenced by age. In the population studied we did not find any association between total, HDL- and LDL-cholesterol and ABO blood groups while triglyceride levels were higher in individuals with B antigen (B + AB) than in subjects without this antigen. We think that environmental factors could be more important than genetic factors in the arousal of cardiovascular diseases.
在本研究中，我们评估了393名年龄在20至59岁之间的意大利男性献血者的总胆固醇、甘油三酯、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇浓度，并研究了这些变量与ABO血型之间的关联。通过多元线性回归，我们发现血清变量浓度的方差受其他血清变量方差的显著影响，而脂质和脂蛋白水平不受年龄的显著影响。在我们研究的人群中，我们未发现总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇与ABO血型之间存在任何关联，而具有B抗原（B+AB）的个体的甘油三酯水平高于没有该抗原的个体。我们认为，在引发心血管疾病方面，环境因素可能比遗传因素更重要。
